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Did you mean mrsa and gla (11 results)?
Altered Sphingolipid Hydrolase Activities and Alpha-Synuclein Level in Late-Onset Schizophrenia.
Usenko T, Bezrukova A, Basharova K, Baydakova G, Shagimardanova E, Blatt N, Rizvanov A, Limankin O, Novitskiy M, Shnayder N, Izyumchenko A, Nikolaev M, Zabotina A, Lavrinova A, Kulabukhova D, Nasyrova R, Palchikova E, Zalutskaya N, Miliukhina I, Barbitoff Y, Glotov O, Glotov A, Taraskina A, Neznanov N, Zakharova E, Pchelina S. Usenko T, et al. Metabolites. 2023 Dec 31;14(1):30. doi: 10.3390/metabo14010030. Metabolites. 2023. PMID: 38248833 Free PMC article.
Additionally, NGS analysis of 11 LSDs genes was conducted in 21 early-onset SCZ patients and 23 controls using the gene panel PGRNseq-NDD. Decreased ASMase, increased GLA activities, and increased HexSpn, LysoGb3, and LysoSM concentrations along with an accumulation of the …
Additionally, NGS analysis of 11 LSDs genes was conducted in 21 early-onset SCZ patients and 23 controls using the gene panel PGRNseq-NDD. D …
A kinetic model for the action of a resistance efflux pump.
Walmsley AR, Zhou T, Borges-Walmsley MI, Rosen BP. Walmsley AR, et al. J Biol Chem. 2001 Mar 2;276(9):6378-91. doi: 10.1074/jbc.M008105200. Epub 2000 Nov 28. J Biol Chem. 2001. PMID: 11096086 Free article.
On the basis of a rigorous analysis of the pre-steady-state kinetics of nucleotide binding and hydrolysis, we propose a model in which ArsA alternates between two mutually exclusive conformations as follows: the ArsA(1) conformation in which the A1 site is closed bu …
On the basis of a rigorous analysis of the pre-steady-state kinetics of nucleotide binding and hydrolysis, we propose a model in which Ar …
Altered autophagy in the mice with a deficiency of saposin A and saposin B.
Sun Y, Grabowski GA. Sun Y, et al. Autophagy. 2013 Jul;9(7):1115-6. doi: 10.4161/auto.24919. Epub 2013 May 6. Autophagy. 2013. PMID: 23697974 Free PMC article.
Saposin B has lipid binding properties and is involved in glycosphingolipid metabolism by presenting the substrates to specific enzymes for degradation, i.e., sulfatide to ARSA/arylsulfatase A, lactosylceramide to GALC/GM-1-beta-galactosylceramidase, and globotriaosylceram …
Saposin B has lipid binding properties and is involved in glycosphingolipid metabolism by presenting the substrates to specific enzymes for …
Antimonite regulation of the ATPase activity of ArsA, the catalytic subunit of the arsenical pump.
Walmsley AR, Zhou T, Borges-Walmsley MI, Rosen BP. Walmsley AR, et al. Biochem J. 2001 Dec 15;360(Pt 3):589-97. doi: 10.1042/0264-6021:3600589. Biochem J. 2001. PMID: 11736648 Free PMC article.
Previously, we have shown the binding and hydrolysis of MgATP to ArsA to be a multi-step process in which the rate-limiting step is an isomerization between different conformational forms of ArsA. This isomerization occurs after product release, at the end of the AT …
Previously, we have shown the binding and hydrolysis of MgATP to ArsA to be a multi-step process in which the rate-limiting step is a …
Variation in 12 porcine genes involved in the carbohydrate moiety assembly of glycosphingolipids does not account for differential binding of F4 Escherichia coli and their fimbriae.
Goetstouwers T, Van Poucke M, Coddens A, Nguyen VU, Melkebeek V, Deforce D, Cox E, Peelman LJ. Goetstouwers T, et al. BMC Genet. 2014 Oct 3;15:103. doi: 10.1186/s12863-014-0103-x. BMC Genet. 2014. PMID: 25277275 Free PMC article.
The aim of this study was to investigate the hypothesis that variation in genes involved in the assembly of the F4 binding carbohydrate moiety of GSLs (i.e. ARSA, B4GALT6, GAL3ST1, GALC, GBA, GLA, GLB1, GLB1L, NEU1, NEU2, UGCG, UGT8) could account for differential b …
The aim of this study was to investigate the hypothesis that variation in genes involved in the assembly of the F4 binding carbohydrate moie …
The ATPase mechanism of ArsA, the catalytic subunit of the arsenite pump.
Walmsley AR, Zhou T, Borges-Walmsley MI, Rosen BP. Walmsley AR, et al. J Biol Chem. 1999 Jun 4;274(23):16153-61. doi: 10.1074/jbc.274.23.16153. J Biol Chem. 1999. PMID: 10347168 Free article.
We propose that the rate-limiting step is an isomerization between different conformational forms of ArsA. kcat is faster than the phosphate burst, indicating that both nucleotide binding sites of ArsA are catalytic. Consistent with this interpretation, approximatel …
We propose that the rate-limiting step is an isomerization between different conformational forms of ArsA. kcat is faster than the ph …